First description of KPC-2-producing Klebsiella oxytoca in Brazil.

نویسندگان

  • Anna C S Almeida
  • Felipe L S Cavalcanti
  • Willames M B Martins
  • Marinalda A Vilela
  • Ana C Gales
  • Marcos A Morais Junior
  • Márcia M C Morais
چکیده

The present work reports the detection of the first case of nosocomial Klebsiella oxytoca producing class A carbapenemase KPC-2 in Brazil. The isolate KPN106 carried a 65-kb IncW-type plasmid that harbors the blaKPC gene and Tn4401b. Moreover, we detected the presence of a class 1 integron containing a new allele, arr-8, followed by a 5'-truncated dhfrIIIc gene. In view of the recent results, we emphasize the high variability of the bacterial and genetic hosts of this resistance determinant.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 57 8  شماره 

صفحات  -

تاریخ انتشار 2013